Video URL: https://www.youtube.com/watch?v=1-NxodiGPCU
The Unseen War in the Microverse
Imagine a hidden world all around you, full of fierce battles. This is the realm of the tiny, where the real rulers of our planet live: microorganisms. We’re talking about creatures like amoebae, protists, bacteria, archaea, and fungi. They’re constantly fighting for space and resources.
And then, there are even stranger things: viruses. These aren’t even considered alive by some, but they hunt everyone else. They aren’t interested in resources; they just want living things to take over. Viruses are the smallest, most common, and deadliest beings on Earth, killing trillions every single day.
What Are Viruses Anyway?
Compared to your cells or even bacteria, viruses are incredibly simple. They are basically:
- A hull (like a shell)
- A tiny bit of genetic material (like instructions)
- A few proteins
They have no metabolism, no way to move themselves, and no ambition or will. They just float around, hoping to bump into something they can infect and take over.
Because they are so simple, scientists argue about whether viruses should be called living things at all.
- Some say viruses are alive.
- Others think the cells they infect are the actual living viruses (calling them viral cells), and the virus particles are more like seeds or spores.
- Many just see viruses as dead material.
The Mystery of Where Viruses Came From
How something that needs a victim to reproduce could even emerge in the first place is a big mystery. There are lots of ideas:
- Maybe viruses were important steps when life first appeared.
- Maybe they started as escaped DNA from cells that got really good at making copies of themselves.
- Maybe they are descendants of really lazy parasites that just let others do all the work.
The current thinking is that viruses probably didn’t just come from one place or time; they likely emerged multiple times from different origins. But we honestly don’t know for sure yet.
Whatever the truth, viruses are incredibly successful. There are an estimated 10,000 billion billion billion viruses on Earth. If you lined them up, they’d stretch for 100 million light years, which is wide enough to span 500 Milky Way galaxies!
Enter the Giants: Giant Viruses (Gyruses)
Things got even weirder for viruses very recently when scientists found a completely new type: giant viruses, nicknamed gyruses.
- They broke all sorts of records for viruses.
- They made scientists question many basic ideas they had about what viruses are like.
Gyruses are so unique they even have their own parasites, called virophages – basically, viruses that hunt other viruses! That seems completely bonkers, right?
Since the first one was found in 2003, it seems these giants are everywhere scientists look: in oceans, water towers, the guts of pigs, and even the mouths of humans. And they’re even stranger than first thought.
What Gyruses Look Like and Where They Were Hiding
Gyruses look kind of funny, often like hairy geometric shapes or mini pickles. The key is they are much larger than all the viruses scientists knew before. This explains how they could have been hiding in plain sight for centuries. Scientists saw them under microscopes but just assumed they must be bacteria. It’s like suddenly finding out there are elephant-sized ducks everywhere!
Most gyruses found so far hunt amoebae and other single-celled beings.
How Gyruses Attack
When a gyrus finds a victim, it connects with it and uses the cell’s own processes to get inside. Like all viruses, their main goal is to take over the victim’s internal setup and make more copies of themselves.
Imagine a tiny mouse crawling into your mouth and using your insides – your guts, bones, and fat tissue – to build a mouse factory. That’s kind of what a gyrus does.
- The gyrus dumps its attack proteins and genetic material inside.
- It rearranges the cell from the inside out.
- The cell’s parts – like its structural elements, protein-making machinery, and lots of mitochondria (for energy) – are changed to become an actual factory called a viroplasm.
- Some gyruses are fancy enough to build a membrane around the viroplasm to protect themselves from the cell’s defenses.
Once the viroplasm factory is ready, it starts building new gyruses, using up the victim from the inside until it’s completely full. Finally, the gyrus usually orders the infected cell to self-destruct, releasing the swarm of new gyruses to find more prey.
Why Gyruses Are So Special
Their size or attack method isn’t what makes gyruses truly special. It’s that they are way more complex than anyone thought possible for a virus.
- Your cells have around 20,000 genes.
- A typical bacterium has a few thousand genes.
- The coronavirus has about 15 genes.
- HIV or the flu virus have around 10 genes.
Now, having a lot of genes isn’t everything (a tomato has 35,000 genes!). But generally, we think of living things as complex systems. Below a certain level of complexity, something might seem more like dead material than a living organism.
But gyruses can have hundreds or even thousands of genes. This really blurs that line between living and dead.
Unique Genes and Potential Metabolism
It’s not just the number of genes that’s special, but also what these genes do. We used to think virus genes were just simple instructions to break into a cell and make more viruses.
But many gyrus genes are completely unique – basically mystery genes that no one understands yet. Even more confusing, a huge number of their genes are things you only expect to see in living things. These are genes needed to:
- Regulate nutrient intake
- Control energy production
- Perform light harvesting
- Handle replication
- Or just generally needed to keep cells alive
Some recent studies have even hinted that some gyruses with very complex genetic codes might be able to maintain a basic level of metabolism on their own. If that turns out to be true, it will completely change what we thought we knew about viruses!
Gyruses and Evolution
We still don’t know anything for sure, but one idea about gyrus genes is that they might fundamentally change how their victims work and evolve. They could do this by:
- Integrating their own genes into the victim’s genetic code, merging into chimeric organisms (a mix of both).
- Or, the other way around, taking some host genes with them and changing themselves.
For billions of years, gyruses might have been living alongside and infecting cells, quietly influencing the development of life. Not just as a simple parasite, but actively jostling evolution in different directions by mixing genes around.
The Stranger Still: Virophages (Viruses Hunting Viruses)
This brings us to another unique thing about gyruses: virophages. These are viruses that hunt gyruses. The whole idea is kind of mind-boggling – how can something that might be dead hunt another thing that might also be dead?
Let’s look at one example: The virophage named Sputnik. Sputnik hunts a gyrus called Mamavirus, which itself hunts amoebae.
- Sputnik is a tiny, simple virus.
- It doesn’t even have the genes or tools to copy itself.
- What it can do is hijack the viroplasm factories created by Mamaviruses inside their amoeba victims.
So, virophages need their victim (the gyrus) to infect its victim (an amoeba) first. Then, they can parasitize the gyrus’s factory inside the amoeba.
When a Mamavirus viroplasm is infected by Sputnik:
- It can only make very few new Mamaviruses.
- Many of those few Mamaviruses are deformed and broken, unable to infect other cells.
- Instead, the factory makes loads of new Sputnik virophages.
Other virophages are even more sneaky. When they infect a viroplasm, they just blend their genetic code into the new gyruses being built, acting like sleeper agents. The next time one of these infiltrated gyruses infects a cell successfully, it mostly produces virophages instead of gyruses!
Defenses in the Microverse
Even giants like gyruses aren’t completely defenseless. A few years ago, the world was amazed by the discovery of CRISPR, a system bacteria use to defend against viruses. It turns out some gyruses might have something similar – a kind of gyrus immune system against virophages.
Interestingly, virophages can also be used as a defense mechanism by living cells against gyruses. Some protists (single-celled organisms) have been found that integrated the genetic code of virophages into their own DNA and kept it. When these protists get infected by gyruses, they use that stored code to create virophages themselves, which then take over the gyrus factories inside the protist.
In the end, the protist would still likely be killed by the gyrus infection. But instead of releasing more gyruses to kill its fellow protists, it releases virophages to hunt those gyruses down!
The Beginning of Discovery
The truly amazing thing about all of this is how new it is. We’ve only known about gyruses and virophages for less than 20 years. We are still very much at the beginning of understanding this tiny, complex world.
Life isn’t just one thing; it’s more like a constant ping pong game involving trillions of different organisms and viruses.
So, if you ever feel like there’s nothing new left to discover, just think about gyruses and all the other elephant-sized ducks that are likely everywhere around us, invisible until we take a closer look!